ITT0131
ITT0131
- Catalog: ITT0131
- Gene/Protein: ADORA2B
- Product Description: Immunotag™ Adenosine A2B-R Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | Adenosine A2B-R |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human ADORA2B. AA range:231-280 |
Specificity | Adenosine A2B-R Polyclonal Antibody detects endogenous levels of Adenosine A2B-R protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | ADORA2B |
Accession No. | P29275 Q60614 |
Alternate Names | ADORA2B; Adenosine receptor A2b |
Description | adenosine A2b receptor(ADORA2B) Homo sapiens This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Calcium,Neuroactive ligand-receptor interaction,Vascular smooth muscle contraction, |
Protein Expression | Brain, |
Subcellular Localization | intracellular,plasma membrane,integral component of plasma membrane,integral component of membrane, |
Protein Function | function:Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |