ITT0133
ITT0133
- Catalog: ITT0133
- Gene/Protein: ADORA3
- Product Description: Immunotag™ Adenosine A3-R Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Adenosine A3-R |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Adenosine A3-R, at AA range: 230-310 |
| Specificity | Adenosine A3-R Polyclonal Antibody detects endogenous levels of Adenosine A3-R protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ADORA3 |
| Accession No. | P33765 Q61618 P28647 |
| Alternate Names | ADORA3; Adenosine receptor A3 |
| Description | adenosine A3 receptor(ADORA3) Homo sapiens This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Alternative splicing results in multiple transcript variants. This gene shares its 5' terminal exon with some transcripts from overlapping GeneID:57413, which encodes an immunoglobulin domain-containing protein. [provided by RefSeq, Nov 2014], |
| Cell Pathway/ Category | Neuroactive ligand-receptor interaction, |
| Protein Expression | Adrenal gland,Brain,Heart,Lung,Testis, |
| Subcellular Localization | plasma membrane,integral component of membrane, |
| Protein Function | function:Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Possible role in reproduction.,PTM:Phosphorylation on Ser-317 may be crucial for rapid desensitization.,similarity:Belongs to the G-protein coupled receptor 1 family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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