ITT0139
ITT0139
- Catalog: ITT0139
- Gene/Protein: MLLT10
- Product Description: Immunotag™ AF-10 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | AF-10 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human AF10. AA range:211-260 |
Specificity | AF-10 Polyclonal Antibody detects endogenous levels of AF-10 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | MLLT10 |
Accession No. | P55197 O54826 |
Alternate Names | MLLT10; AF10; Protein AF-10; ALL1-fused gene from chromosome 10 protein |
Description | myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10(MLLT10) Homo sapiens This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010], |
Protein Expression | Brain,Human rectum tumor,Liver,Ovary, |
Subcellular Localization | nucleus,nucleoplasm,cytoplasm,protein complex, |
Protein Function | disease:A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t(10;11)(p12;q23) with MLL/HRX. The result is a rogue activator protein.,disease:A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t(10;11)(p13;q14) with PICALM.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 2 PHD-type zinc fingers.,tissue specificity:Expressed abundantly in testis., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |