ITT0151
ITT0151
- Catalog: ITT0151
- Gene/Protein: AIM2
- Product Description: Immunotag™ AIM2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | AIM2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human AIM2. AA range:51-100 |
| Specificity | AIM2 Polyclonal Antibody detects endogenous levels of AIM2 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | AIM2 |
| Accession No. | O14862 Q91VJ1 |
| Alternate Names | AIM2; Interferon-inducible protein AIM2; Absent in melanoma 2 |
| Description | absent in melanoma 2(AIM2) Homo sapiens AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Cytosolic DNA-sensing pathway, |
| Protein Expression | Brain,Spleen, |
| Subcellular Localization | nucleus,cytoplasm,cytosol,AIM2 inflammasome complex, |
| Protein Function | disease:Defects in AIM2 may be a cause of microsatellite unstable colon cancers.,function:Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.,induction:By interferon gamma.,similarity:Belongs to the HIN-200 family.,similarity:Contains 1 DAPIN domain.,similarity:Contains 1 HIN-200 domain.,subunit:Homodimer.,tissue specificity:Expressed in spleen, small intestine, peripheral blood leukocytes, and testis., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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