ITT0223
ITT0223
- Catalog: ITT0223
- Gene/Protein: MYCBP
- Product Description: Immunotag™ AMY-1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | AMY-1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from AMY-1 . at AA range: 30-110 |
| Specificity | AMY-1 Polyclonal Antibody detects endogenous levels of AMY-1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | MYCBP |
| Accession No. | Q99417 Q9EQS3 |
| Alternate Names | MYCBP; AMY1; C-Myc-binding protein; Associate of Myc 1; AMY-1 |
| Description | MYC binding protein(MYCBP) Homo sapiens The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene. [provided by RefSeq, Nov 2011], |
| Protein Expression | Eye,Placenta,Platelet, |
| Subcellular Localization | nucleus,cytoplasm,mitochondrion, |
| Protein Function | function:May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC.,similarity:Belongs to the AMY1 family.,subcellular location:Translocates into the nucleus in the S phase of the cell cycle upon an increase of c-Myc expression. Found in the mitochondria when associated with AKAP1.,subunit:Binds via its C-terminal region to the N-terminal region of MYC. Associates with AKAP1/S-AKAP84. Interacts with MYCBPAP.,tissue specificity:Highly expressed in heart, placenta, pancreas, skeletal muscle and kidney. Also present at low levels in lung., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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