ITT0228
ITT0228
- Catalog: ITT0228
- Gene/Protein: AMOTL1
- Product Description: Immunotag™ Angiomotin-L1 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | Angiomotin-L1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human AMOTL1. AA range:441-490 |
Specificity | Angiomotin-L1 Polyclonal Antibody detects endogenous levels of Angiomotin-L1 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | AMOTL1 |
Accession No. | Q8IY63 Q9D4H4 |
Alternate Names | AMOTL1; Angiomotin-like protein 1 |
Description | angiomotin like 1(AMOTL1) Homo sapiens The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014], |
Cell Pathway/ Category | Tight junction, |
Protein Expression | Brain,Epithelium,Muscle,Skeletal muscle,Skin,Spleen,Testis,Thymus, |
Subcellular Localization | cytoplasm,cytosol,bicellular tight junction,COP9 signalosome,apical plasma membrane,lamellipodium,cell junction,cytoplasmic vesicle, |
Protein Function | similarity:Belongs to the angiomotin family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |