ITT0261
ITT0261
- Catalog: ITT0261
- Gene/Protein: ANAPC1
- Product Description: Immunotag™ APC1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | APC1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human APC1. AA range:321-370 |
| Specificity | APC1 Polyclonal Antibody detects endogenous levels of APC1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ANAPC1 |
| Accession No. | Q9H1A4 P53995 |
| Alternate Names | ANAPC1; TSG24; Anaphase-promoting complex subunit 1; APC1; Cyclosome subunit 1; Mitotic checkpoint regulator; Testis-specific gene 24 protein |
| Description | anaphase promoting complex subunit 1(ANAPC1) Homo sapiens This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011], |
| Cell Pathway/ Category | Cell_Cycle_G1S,Cell_Cycle_G2M_DNA,Oocyte meiosis,Ubiquitin mediated proteolysis,Progesterone-mediated oocyte maturation, |
| Protein Expression | Colon,Epithelium,Ovary,Placenta, |
| Subcellular Localization | nucleoplasm,anaphase-promoting complex,cytosol, |
| Protein Function | function:Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.,pathway:Protein modification; protein ubiquitination.,PTM:Phosphorylated. Phosphorylation on Ser-355 occurs specifically during mitosis.,similarity:Belongs to the APC1 family.,similarity:Contains 4 PC repeats.,subunit:The APC/C is composed of at least 11 subunits., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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