ITT0319
ITT0319
- Catalog: ITT0319
- Gene/Protein: ARHGAP23
- Product Description: Immunotag™ ARHGAP23 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | ARHGAP23 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,WB,ELISA |
Recommended Dilution | WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from ARHGAP23 . at AA range: 470-550 |
Specificity | ARHGAP23 Polyclonal Antibody detects endogenous levels of ARHGAP23 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | ARHGAP23 |
Accession No. | Q9P227 Q69ZH9 |
Alternate Names | ARHGAP23; KIAA1501; Rho GTPase-activating protein 23; Rho-type GTPase-activating protein 23 |
Description | Rho GTPase activating protein 23(ARHGAP23) Homo sapiens The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins, such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP (Katoh and Katoh, 2004 [PubMed 15254754]).[supplied by OMIM, Mar 2008], |
Protein Expression | Brain, |
Subcellular Localization | cytosol,extracellular exosome, |
Protein Function | function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 Rho-GAP domain.,tissue specificity:Expressed in placenta, prostate, hippocampus and brain medulla. Also expressed in brain tumor, salivary gland tumor, head and neck tumor., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |