ITT0453
ITT0453
- Catalog: ITT0453
- Gene/Protein: ARL2BP
- Product Description: Immunotag™ BART1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | BART1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from BART1, at AA range: 70-150 |
| Specificity | BART1 Polyclonal Antibody detects endogenous levels of BART1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ARL2BP |
| Accession No. | Q9Y2Y0 Q9D385 Q4V8C5 |
| Alternate Names | ARL2BP; BART; BART1; ADP-ribosylation factor-like protein 2-binding protein; ARF-like 2-binding protein; Binder of ARF2 protein 1 |
| Description | ADP ribosylation factor like GTPase 2 binding protein(ARL2BP) Homo sapiens ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. [provided by RefSeq, Jul 2008], |
| Protein Expression | Brain,Mammary gland, |
| Subcellular Localization | nucleus,mitochondrial intermembrane space,mitochondrial matrix,centrosome,spindle,cytosol,cilium,midbody, |
| Protein Function | function:May play a role as an effector of the ADP-ribosylation factor-like protein 2, ARL2.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the ARL2BP family.,subunit:Interacts with GTP bound ARL2 and ARL3; the complex ARL2-ARL2BP as well as ARL2BP alone, binds to ANT1.,tissue specificity:Ubiquitous., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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