ITT0472
ITT0472
- Catalog: ITT0472
- Gene/Protein: BCL2L12
- Product Description: Immunotag™ BCL2L12 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Bcl-2L12 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from BCL2L12 . at AA range: 60-140 |
| Specificity | BCL2L12 Polyclonal Antibody detects endogenous levels of BCL2L12 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | BCL2L12 |
| Accession No. | Q9HB09 |
| Alternate Names | BCL2L12; BPR; Bcl-2-like protein 12; Bcl2-L-12; Bcl-2-related proline-rich protein |
| Description | BCL2 like 12(BCL2L12) Homo sapiens This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013], |
| Protein Expression | Epithelium,PCR rescued clones,Uterus, |
| Subcellular Localization | nucleus,membrane, |
| Protein Function | similarity:Belongs to the Bcl-2 family.,tissue specificity:Expressed mainly in breast, thymus, prostate, fetal liver, colon, placenta, pancreas, small intestine, spinal cord, kidney, and bone marrow and to a lesser extent in many other tissues. Isoform 2 is primarily expressed in skeletal muscle., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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