ITT0527
ITT0527
- Catalog: ITT0527
- Gene/Protein: BRMS1
- Product Description: Immunotag™ BRMS-1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | BRMS-1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from BRMS-1, at AA range: 40-120 |
| Specificity | BRMS-1 Polyclonal Antibody detects endogenous levels of BRMS-1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | BRMS1 |
| Accession No. | Q9HCU9 Q99N20 Q5M7T3 |
| Alternate Names | BRMS1; Breast cancer metastasis-suppressor 1 |
| Description | breast cancer metastasis suppressor 1(BRMS1) Homo sapiens This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008], |
| Protein Expression | Brain,Kidney,Placenta, |
| Subcellular Localization | nucleus,nucleoplasm,cytoplasm,Sin3-type complex, |
| Protein Function | function:May be a mediator of metastasis suppression in breast carcinoma.,similarity:Belongs to the BRMS1 family.,tissue specificity:Expression levels are higher in term placentas than in early placentas. Low levels of expression observed in normal pregnancies and in molar pregnancies., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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