ITT0529
ITT0529
- Catalog: ITT0529
- Gene/Protein: POU4F1
- Product Description: Immunotag™ Brn-3a Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | BRN-3a |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Brn-3a, at AA range: 280-360 |
| Specificity | Brn-3a Polyclonal Antibody detects endogenous levels of Brn-3a protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | POU4F1 |
| Accession No. | Q01851 P17208 P20266 |
| Alternate Names | POU4F1; BRN3A; RDC1; POU domain; class 4, transcription factor 1; Brain-specific homeobox/POU domain protein 3A; Brain-3A; Brn-3A; Homeobox/POU domain protein RDC-1; Oct-T1 |
| Description | POU class 4 homeobox 1(POU4F1) Homo sapiens This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some adult acute myeloid leukemias. [provided by RefSeq, Mar 2012], |
| Protein Expression | Placenta,Retina, |
| Subcellular Localization | nuclear chromatin,nucleoplasm,neuron projection, |
| Protein Function | developmental stage:Expression peaks early in embryogenesis (day 13.5) and is undetectable 14 days after birth.,function:Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons.,similarity:Belongs to the POU transcription factor family. Class-4 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,tissue specificity:Brain. Seems to be specific to the retina. Present in the developing brain, spinal cord and eye., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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