ITT0537
ITT0537
- Catalog: ITT0537
- Gene/Protein: ZMYND11
- Product Description: Immunotag™ BS69 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | BS69 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human ZMY11. AA range:111-160 |
Specificity | BS69 Polyclonal Antibody detects endogenous levels of BS69 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | ZMYND11 |
Accession No. | Q15326 Q8R5C8 |
Alternate Names | ZMYND11; BS69; Zinc finger MYND domain-containing protein 11; Adenovirus 5 E1A-binding protein; Protein BS69 |
Description | zinc finger MYND-type containing 11(ZMYND11) Homo sapiens The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008], |
Protein Expression | Brain,Colon carcinoma,Pancreas,Peripheral Nervous System, |
Subcellular Localization | nucleus,nucleoplasm,chromosome,integral component of membrane, |
Protein Function | function:Binds to the transactivation domain of the adenovirus type 5 E1A 32 kDa protein (289R) and inhibits its transactivating activity. May act as tumor suppressor through suppression of adenovirus replication.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 bromo domain.,similarity:Contains 1 MYND-type zinc finger.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 PWWP domain., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |