ITT0548
ITT0548
- Catalog: ITT0548
- Gene/Protein: BUB3
- Product Description: Immunotag™ Bub3 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | BUB3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BUB3. AA range:279-328 |
| Specificity | Bub3 Polyclonal Antibody detects endogenous levels of Bub3 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | BUB3 |
| Accession No. | O43684 Q9WVA3 |
| Alternate Names | BUB3; Mitotic checkpoint protein BUB3 |
| Description | BUB3, mitotic checkpoint protein(BUB3) Homo sapiens This gene encodes a protein involved in spindle checkpoint function. The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Cell_Cycle_G1S,Cell_Cycle_G2M_DNA, |
| Protein Expression | Brain,Epithelium,Placenta,Spleen,Testis, |
| Subcellular Localization | kinetochore,condensed chromosome kinetochore,nucleoplasm,cytosol,mitotic checkpoint complex,bub1-bub3 complex, |
| Protein Function | function:Required for kinetochore localization of BUB1.,similarity:Belongs to the WD repeat BUB3 family.,similarity:Contains 5 WD repeats.,subunit:Interacts with BUB1 and BUBR1., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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