ITT0571
ITT0571
- Catalog: ITT0571
- Gene/Protein: C9
- Product Description: Immunotag™ C9 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | C9 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human C9. AA range:181-230 |
| Specificity | C9 Polyclonal Antibody detects endogenous levels of C9 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | C9 |
| Accession No. | P02748 P06683 |
| Alternate Names | C9; Complement component C9 |
| Description | complement C9(C9) Homo sapiens This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. [provided by RefSeq, Feb 2009], |
| Cell Pathway/ Category | Complement and coagulation cascades,Prion diseases,Systemic lupus erythematosus, |
| Protein Expression | Blood,Liver,Plasma,Platelet, |
| Subcellular Localization | extracellular region,membrane attack complex,cytoplasm,plasma membrane,integral component of plasma membrane,integral component of membrane,extracellular exosome,blood microparticle, |
| Protein Function | disease:Defects in C9 are a cause of component C9 deficiency (C9D) [MIM:120940]. Patients with C9D suffer from recurrent bacterial infections, predominantly from Neisseria meningitidis.,function:C9 is the final component of the complement system to be added in the assembly of the membrane attack complex. It is able to enter lipid bilayers, forming transmembrane channels.,online information:C9 mutation db,PTM:Thrombin cleaves factor C9 to produce C9a and C9b.,similarity:Belongs to the complement C6/C7/C8/C9 family.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 LDL-receptor class A domain.,similarity:Contains 1 MACPF domain.,similarity:Contains 1 TSP type-1 domain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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