ITT0582
ITT0582
- Catalog: ITT0582
- Gene/Protein: CA14
- Product Description: Immunotag™ CA XIV Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | CA XIV |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human CA14. AA range:161-210 |
Specificity | CA XIV Polyclonal Antibody detects endogenous levels of CA XIV protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | CA14 |
Accession No. | Q9ULX7 Q9WVT6 |
Alternate Names | CA14; Carbonic anhydrase 14; Carbonate dehydratase XIV; Carbonic anhydrase XIV; CA-XIV |
Description | carbonic anhydrase 14(CA14) Homo sapiens Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XIV is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Nitrogen metabolism, |
Protein Expression | Brain,Heart,Lung,Testis, |
Subcellular Localization | plasma membrane,integral component of membrane, |
Protein Function | catalytic activity:H(2)CO(3) = CO(2) + H(2)O.,cofactor:Zinc.,function:Reversible hydration of carbon dioxide.,similarity:Belongs to the alpha-carbonic anhydrase family.,tissue specificity:High expression in all parts of the central nervous system and lower expression in adult liver, heart, small intestine, colon, kidney, urinary bladder and skeletal muscle., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |