ITT0597
ITT0597
- Catalog: ITT0597
- Gene/Protein: CDH20
- Product Description: Immunotag™ Cadherin-20 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Cadherin-20 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,IF,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Cadherin-20, at AA range: 80-160 |
| Specificity | Cadherin-20 Polyclonal Antibody detects endogenous levels of Cadherin-20 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CDH20 |
| Accession No. | Q9HBT6 Q9Z0M3 Q5DWV1 |
| Alternate Names | CDH20; CDH7L3; Cadherin-20 |
| Description | cadherin 20(CDH20) Homo sapiens This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Adherens_Junction |
| Protein Expression | Cerebellum, |
| Subcellular Localization | plasma membrane,integral component of membrane, |
| Protein Function | function:Cadherins are calcium dependent cell adhesion proteins.,function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 5 cadherin domains.,tissue specificity:Expressed in placenta, adult brain, and fetal brain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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