ITT0598
ITT0598
- Catalog: ITT0598
- Gene/Protein: CDH22
- Product Description: Immunotag™ Cadherin-22 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | Cadherin-22 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from Cadherin-22, at AA range: 80-160 |
Specificity | Cadherin-22 Polyclonal Antibody detects endogenous levels of Cadherin-22 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | CDH22 |
Accession No. | Q9UJ99 Q9WTP5 Q63315 |
Alternate Names | CDH22; C20orf25; Cadherin-22; Pituitary and brain cadherin; PB-cadherin |
Description | cadherin 22(CDH22) Homo sapiens This gene is a member of the cadherin superfamily. The gene product is composed of five cadherin repeat domains and a cytoplasmic tail similar to the highly conserved cytoplasmic region of classical cadherins. Expressed predominantly in the brain, this putative calcium-dependent cell adhesion protein may play an important role in morphogenesis and tissue formation in neural and non-neural cells during development and maintenance of the brain and neuroendocrine organs. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Adherens_Junction |
Protein Expression | Brain,Testis, |
Subcellular Localization | plasma membrane,integral component of membrane, |
Protein Function | function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. PB-cadherins may have a role in the morphological organization of pituitary gland and brain tissues.,similarity:Contains 5 cadherin domains., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |