ITT0611
ITT0611
- Catalog: ITT0611
- Gene/Protein: CALML5
- Product Description: Immunotag™ CALML5 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CALML5 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CALML5. AA range:96-146 |
| Specificity | CALML5 Polyclonal Antibody detects endogenous levels of CALML5 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CALML5 |
| Accession No. | Q9NZT1 |
| Alternate Names | CALML5; CLSP; Calmodulin-like protein 5; Calmodulin-like skin protein |
| Description | calmodulin like 5(CALML5) Homo sapiens This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Calcium,Phosphatidylinositol signaling system,Oocyte meiosis,Vascular smooth muscle contraction,Long-term potentiation,Neurotrophin,Olfactory transduction,Insulin_Receptor,GnRH,Melanogenesis,Alzheimer's disease,Glioma, |
| Protein Expression | Dermoid cancer,Hepatoma,Skin, |
| Subcellular Localization | extracellular exosome, |
| Protein Function | function:Binds calcium. May be involved in terminal differentiation of keratinocytes.,similarity:Contains 4 EF-hand domains.,subunit:Associates with transglutaminase 3.,tissue specificity:Particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation. Very low expression in lung., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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