ITT0683
ITT0683
- Catalog: ITT0683
- Gene/Protein: CTSG
- Product Description: Immunotag™ Cathepsin G Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CathEPSin G |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Cathepsin G. AA range:67-116 |
| Specificity | Cathepsin G Polyclonal Antibody detects endogenous levels of Cathepsin G protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CTSG |
| Accession No. | P08311 P28293 |
| Alternate Names | CTSG; Cathepsin G; CG |
| Description | cathepsin G(CTSG) Homo sapiens The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Sep 2014], |
| Cell Pathway/ Category | Neuroactive ligand-receptor interaction,Lysosome,Renin-angiotensin system,Systemic lupus erythematosus, |
| Protein Expression | Monocyte,Neutrophil,Skin, |
| Subcellular Localization | extracellular region,extracellular space,nucleus,plasma membrane,cell surface,secretory granule,extracellular matrix,extracellular exosome, |
| Protein Function | catalytic activity:Specificity similar to chymotrypsin C.,enzyme regulation:Inhibited by soybean trypsin inhibitor, benzamidine, the synthetic peptide R13K, Z-Gly-Leu-Phe-CH2Cl and phenylmethylsulfonyl fluoride. Inhibited by LPS from P.aeruginosa but not by LPS from S.minnesota.,function:Serine protease with trypsin- and chymotrypsin-like specificity. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe-CH2Cl and phenylmethylsulfonyl fluoride.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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