ITT0758
ITT0758
- Catalog: ITT0758
- Gene/Protein: ENTPD1
- Product Description: Immunotag™ CD39 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | CD39 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ENTPD1. AA range:351-400 |
| Specificity | CD39 Polyclonal Antibody detects endogenous levels of CD39 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ENTPD1 |
| Accession No. | P49961 P55772 |
| Alternate Names | ENTPD1; CD39; Ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; Ecto-ATP diphosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen; CD antigen CD39 |
| Description | ectonucleoside triphosphate diphosphohydrolase 1(ENTPD1) Homo sapiens The protein encoded by this gene is a plasma membrane protein that hydrolyzes extracellular ATP and ADP to AMP. Inhibition of this protein's activity may confer anticancer benefits. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015], |
| Cell Pathway/ Category | Purine metabolism,Pyrimidine metabolism, |
| Protein Expression | Brain,Liver,Lung,Placenta,Synovial membrane tissue, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,membrane,integral component of membrane,extracellular exosome, |
| Protein Function | catalytic activity:ATP + 2 H(2)O = AMP + 2 phosphate.,cofactor:Calcium.,cofactor:Magnesium.,function:In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation. Hydrolyzes ATP and ADP equally well.,PTM:Palmitoylated in the N-terminal part.,PTM:The N-terminus is blocked.,similarity:Belongs to the GDA1/CD39 NTPase family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. The vascular isoform and the placental isoform II are present in both placenta and umbilical vein, whereas placental isoform I is present in placenta only., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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