ITT0770
ITT0770
- Catalog: ITT0770
- Gene/Protein: CD58
- Product Description: Immunotag™ CD58 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CD58 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human LFA3. AA range:36-85 |
| Specificity | CD58 Polyclonal Antibody detects endogenous levels of CD58 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CD58 |
| Accession No. | P19256 |
| Alternate Names | CD58; LFA3; Lymphocyte function-associated antigen 3; Ag3; Surface glycoprotein LFA-3; CD antigen CD58 |
| Description | CD58 molecule(CD58) Homo sapiens This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009], |
| Cell Pathway/ Category | Cell adhesion molecules (CAMs), |
| Protein Expression | Brain,Erythrocyte, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,cell surface,membrane,integral component of membrane,anchored component of membrane,extracellular exosome, |
| Protein Function | function:Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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