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ITT0780

ITT0780
  • Gene/Protein: LILRB5
  • Product Description: Immunotag™ CD85c Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ CD85c Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein CD8500c
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application IHC-p,ELISA
Recommended Dilution Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen Synthesized peptide derived from the Internal region of human CD85c.
Specificity CD85c Polyclonal Antibody detects endogenous levels of CD85c protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name LILRB5
Accession No. O75023
Alternate Names LILRB5; LIR8; Leukocyte immunoglobulin-like receptor subfamily B member 5; CD85 antigen-like family member C; Leukocyte immunoglobulin-like receptor 8; LIR-8; CD antigen CD85c
Description leukocyte immunoglobulin like receptor B5(LILRB5) Homo sapiens This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Protein Expression Pancreas,Peripheral blood leukocyte,Plasma,Small intestine,
Subcellular Localization integral component of membrane,
Protein Function domain:Contains 2 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.,function:May act as receptor for class I MHC antigens.,similarity:Contains 4 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Detected in a natural killer (NK) cells.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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