ITT0810
ITT0810
- Catalog: ITT0810
- Gene/Protein: CDC42EP4
- Product Description: Immunotag™ Cdc42EP4 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CDC42EP4 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BORG4. AA range:201-250 |
| Specificity | Cdc42EP4 Polyclonal Antibody detects endogenous levels of Cdc42EP4 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CDC42EP4 |
| Accession No. | Q9H3Q1 Q9JM96 |
| Alternate Names | CDC42EP4; BORG4; CEP4; Cdc42 effector protein 4; Binder of Rho GTPases 4 |
| Description | CDC42 effector protein 4(CDC42EP4) Homo sapiens The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008], |
| Protein Expression | Brain,Epithelium,Eye,Ileal mucosa,Mammary gland,Skin,Tongue, |
| Subcellular Localization | cytoplasm,plasma membrane,cell-cell junction,endomembrane system,actin cytoskeleton,microtubule cytoskeleton, |
| Protein Function | function:Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts.,similarity:Belongs to the BORG/CEP family.,similarity:Contains 1 CRIB domain.,subunit:Interacts with CDC42 and RHOQ, in a GTP-dependent manner.,tissue specificity:Not detected in any of the adult tissues tested. May be expressed only in fetal or embryonic tissues., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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