ITT0889
ITT0889
- Catalog: ITT0889
- Gene/Protein: CGGBP1
- Product Description: Immunotag™ CGGBP1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CGGBP1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CGGBP1. AA range:41-90 |
| Specificity | CGGBP1 Polyclonal Antibody detects endogenous levels of CGGBP1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CGGBP1 |
| Accession No. | Q9UFW8 Q8BHG9 |
| Alternate Names | CGGBP1; CGGBP; CGG triplet repeat-binding protein 1; CGG-binding protein 1; 20 kDa CGG-binding protein; p20-CGGBP DNA-binding protein |
| Description | CGG triplet repeat binding protein 1(CGGBP1) Homo sapiens CGGBP1 influences expression of the FMR1 gene (MIM 309550), which is associated with the fragile X mental retardation syndrome (MIM 300624), by specifically interacting with the 5-prime (CGG)n-3-prime repeat in its 5-prime UTR.[supplied by OMIM, Mar 2008], |
| Protein Expression | Kidney,Melanocyte,Testis, |
| Subcellular Localization | nucleus,nucleoplasm, |
| Protein Function | developmental stage:Expressed in fetal brain and kidney. Lower expression in fetal liver and lung.,function:Binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. May play a role in regulating FMR1 promoter.,miscellaneous:Binding is severely inhibited by complete or partial cytosine-specific DNA methylation of the binding motif.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,tissue specificity:Ubiquitous. Highly expressed in placenta, thymus, lymph nodes, cerebellum and cerebral cortex. Low expression in other regions of the brain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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