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ITT0891

ITT0891-2
ITT0891
ITT0891-2
ITT0891
ITT0891
  • Gene/Protein: PRKG2
  • Product Description: Immunotag™ cGKII Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ cGKII Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein cGKII
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen Synthesized peptide derived from cGKII, at AA range: 70-150
Specificity cGKII Polyclonal Antibody detects endogenous levels of cGKII protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name PRKG2
Accession No. Q13237 Q61410 Q64595
Alternate Names PRKG2; PRKGR2; cGMP-dependent protein kinase 2; cGK 2; cGK2; cGMP-dependent protein kinase II; cGKII
Description protein kinase, cGMP-dependent, type II(PRKG2) Homo sapiens This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
Cell Pathway/ Category Gap junction,Long-term depression,Olfactory transduction,
Protein Expression Pituitary,
Subcellular Localization cytosol,apical plasma membrane,nuclear membrane,
Protein Function catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Binding of cGMP results in enzyme activation.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 cyclic nucleotide-binding domains.,tissue specificity:Highly concentrated in brain, lung and intestinal mucosa.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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