ITT0979
ITT0979
- Catalog: ITT0979
- Gene/Protein: PDLIM1
- Product Description: Immunotag™ CLP36 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | CLP36 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from CLP36, at AA range: 30-110 |
Specificity | CLP36 Polyclonal Antibody detects endogenous levels of CLP36 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | PDLIM1 |
Accession No. | O00151 O70400 P52944 |
Alternate Names | PDLIM1; CLIM1; CLP36; PDZ and LIM domain protein 1; C-terminal LIM domain protein 1; Elfin; LIM domain protein CLP-36 |
Description | PDZ and LIM domain 1(PDLIM1) Homo sapiens This gene encodes a member of the enigma protein family. The protein contains two protein interacting domains, a PDZ domain at the amino terminal end and one to three LIM domains at the carboxyl terminal. It is a cytoplasmic protein associated with the cytoskeleton. The protein may function as an adapter to bring other LIM-interacting proteins to the cytoskeleton. Pseudogenes associated with this gene are located on chromosomes 3, 14 and 17. [provided by RefSeq, Oct 2012], |
Protein Expression | Epithelium,Heart,Pancreas,Placenta,Platelet,T-cell, |
Subcellular Localization | transcription factor complex,cytoplasm,cytoskeleton,cell-cell adherens junction,focal adhesion, |
Protein Function | function:Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton.,similarity:Contains 1 LIM zinc-binding domain.,similarity:Contains 1 PDZ (DHR) domain.,subcellular location:Associates with the actin stress fibers.,subunit:Interacts with alpha-actinins 1, 2 and 4.,tissue specificity:Strongly expressed in the heart and skeletal muscle, moderately expressed in the spleen, small intestine, colon, placenta, and lung. A lower level expression is seen in liver, thymus, kidney, prostate and pancreas and is not found in the brain, testis, ovary, and peripheral blood leukocytes., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |