ITT1055
ITT1055
- Catalog: ITT1055
- Gene/Protein: CNTN5
- Product Description: Immunotag™ Contactin 5 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | Contactin 5 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IF,IHC-p,ELISA |
Recommended Dilution | Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human CNTN5. AA range:891-940 |
Specificity | Contactin 5 Polyclonal Antibody detects endogenous levels of Contactin 5 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | CNTN5 |
Accession No. | O94779 P68500 |
Alternate Names | CNTN5; Contactin-5; Neural recognition molecule NB-2; hNB-2 |
Description | contactin 5(CNTN5) Homo sapiens The protein encoded by this gene is a member of the immunoglobulin superfamily, and contactin family, which mediate cell surface interactions during nervous system development. This protein is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011], |
Protein Expression | Brain,Cerebellum, |
Subcellular Localization | cytoplasm,plasma membrane,anchored component of membrane, |
Protein Function | function:Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system.,similarity:Belongs to the immunoglobulin superfamily. Contactin family.,similarity:Contains 4 fibronectin type-III domains.,similarity:Contains 6 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Expressed in brain and kidney and at very low level in placenta. Not expressed in other tissues. In brain, it is highly expressed in the occipital lobe, amygdala, cerebral cortex, frontal lobe, thalamus and temporal lobe. Expressed at moderate level in the cerebellum, substantia nigra, putamen, medulla and hippocampus. Weakly expressed in the spinal cord and caudate nucleus. Weakly or not expressed in the corpus callosum., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |