ITT1076
ITT1076
- Catalog: ITT1076
- Gene/Protein: COX5A
- Product Description: Immunotag™ COX5a Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | COX5a |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from COX5a, at AA range: 40-120 |
| Specificity | COX5a Polyclonal Antibody detects endogenous levels of COX5a protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | COX5A |
| Accession No. | P20674 P12787 P11240 |
| Alternate Names | COX5A; Cytochrome c oxidase subunit 5A; mitochondrial; Cytochrome c oxidase polypeptide Va |
| Description | cytochrome c oxidase subunit 5A(COX5A) Homo sapiens Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Oxidative phosphorylation,Cardiac muscle contraction,Alzheimer's disease,Parkinson's disease,Huntington's disease, |
| Protein Expression | Brain,Heart,Liver, |
| Subcellular Localization | mitochondrial inner membrane,mitochondrial respiratory chain complex IV,myelin sheath,extracellular exosome, |
| Protein Function | function:This is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.,similarity:Belongs to the cytochrome c oxidase subunit 5A family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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