ITT1088
ITT1088
- Catalog: ITT1088
- Gene/Protein: CPM
- Product Description: Immunotag™ CPM Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | CPM |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human CPM. AA range:71-120 |
Specificity | CPM Polyclonal Antibody detects endogenous levels of CPM protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | CPM |
Accession No. | P14384 Q80V42 |
Alternate Names | CPM; Carboxypeptidase M; CPM |
Description | carboxypeptidase M(CPM) Homo sapiens The protein encoded by this gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 potential asparagine-linked glycosylation sites. The active site residues of carboxypeptidases A and B are conserved in this protein. Three alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008], |
Protein Expression | Liver,Lung,Placenta, |
Subcellular Localization | extracellular space,plasma membrane,cell surface,integral component of membrane,anchored component of membrane,extracellular exosome, |
Protein Function | catalytic activity:Cleavage of C-terminal arginine or lysine residues from polypeptides.,cofactor:Binds 1 zinc ion per subunit.,enzyme regulation:Inhibited by O-phenanthroline and MGTA and activated by cobalt.,function:Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins.,similarity:Belongs to the peptidase M14 family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |