ITT1091
ITT1091
- Catalog: ITT1091
- Gene/Protein: CPT1B
- Product Description: Immunotag™ CPTI-M Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CPTI-M |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CPT1B. AA range:401-450 |
| Specificity | CPTI-M Polyclonal Antibody detects endogenous levels of CPTI-M protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CPT1B |
| Accession No. | Q92523 Q924X2 |
| Alternate Names | CPT1B; KIAA1670; Carnitine O-palmitoyltransferase 1; muscle isoform; CPT1-M; Carnitine O-palmitoyltransferase I, muscle isoform; CPT I; CPTI-M; Carnitine palmitoyltransferase 1B; Carnitine palmitoyltransferase I-like protein |
| Description | carnitine palmitoyltransferase 1B(CPT1B) Homo sapiens The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009], |
| Cell Pathway/ Category | Fatty acid metabolism,Glycerophospholipid metabolism,PPAR,Adipocytokine, |
| Protein Expression | Brain,Clones donated by RIKEN,Epithelium,Heart,Human lung,Lung,Skel |
| Subcellular Localization | mitochondrion,mitochondrial outer membrane,integral component of membrane, |
| Protein Function | catalytic activity:ATP + choline = ADP + O-phosphocholine.,catalytic activity:ATP + ethanolamine = ADP + O-phosphoethanolamine.,catalytic activity:Palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine.,miscellaneous:This protein is produced by a bicistronic gene which also produces the CHKB protein from a non-overlapping reading frame.,miscellaneous:This protein is produced by a bicistronic gene which also produces the CPT1B protein from a non-overlapping reading frame.,pathway:Lipid metabolism; fatty acid beta-oxidation.,similarity:Belongs to the carnitine/choline acetyltransferase family.,similarity:Belongs to the choline/ethanolamine kinase family.,tissue specificity:Strong expression in heart and skeletal muscle. No expression in liver and kidney., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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