ITT1118
ITT1118
- Catalog: ITT1118
- Gene/Protein: CROT
- Product Description: Immunotag™ CROT Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CROT |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from CROT, at AA range: 190-270 |
| Specificity | CROT Polyclonal Antibody detects endogenous levels of CROT protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CROT |
| Accession No. | Q9UKG9 Q9DC50 P11466 |
| Alternate Names | CROT; COT; Peroxisomal carnitine O-octanoyltransferase; COT |
| Description | carnitine O-octanoyltransferase(CROT) Homo sapiens This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009], |
| Protein Expression | Brain,Skin, |
| Subcellular Localization | mitochondrion,peroxisome,peroxisomal matrix,intracellular membrane-bounded organelle, |
| Protein Function | catalytic activity:Octanoyl-CoA + L-carnitine = CoA + L-octanoylcarnitine.,function:Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate. Converts the end product of pristanic acid beta oxidation, 4,8-dimethylnonanoyl-CoA, to its corresponding carnitine ester.,pathway:Lipid metabolism; fatty acid beta-oxidation.,similarity:Belongs to the carnitine/choline acetyltransferase family.,subunit:Monomer., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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