ITT1249
ITT1249
- Catalog: ITT1249
- Gene/Protein: CSTA
- Product Description: Immunotag™ Cystatin A Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | CySTATin A |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human Stefin A. AA range:49-98 |
Specificity | Cystatin A Polyclonal Antibody detects endogenous levels of Cystatin A protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | CSTA |
Accession No. | P01040 P56567 |
Alternate Names | CSTA; STF1; STFA; Cystatin-A; Cystatin-AS; Stefin-A |
Description | cystatin A(CSTA) Homo sapiens The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer. [provided by RefSeq, Jul 2008], |
Protein Expression | Bone marrow,Keratinocyte,Tongue, |
Subcellular Localization | cornified envelope,extracellular space,intracellular,nucleus,cytoplasm,extracellular matrix,extracellular exosome, |
Protein Function | function:This is an intracellular thiol proteinase inhibitor.,similarity:Belongs to the cystatin family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |