ITT1257
ITT1257
- Catalog: ITT1257
- Gene/Protein: CYB5A
- Product Description: Immunotag™ Cytochrome b5 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Cytochrome b5 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Cytochrome b5, at AA range: 30-110 |
| Specificity | Cytochrome b5 Polyclonal Antibody detects endogenous levels of Cytochrome b5 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CYB5A |
| Accession No. | P00167 P56395 P00173 |
| Alternate Names | CYB5A; CYB5; Cytochrome b5; Microsomal cytochrome b5 type A; MCB5 |
| Description | cytochrome b5 type A(CYB5A) Homo sapiens The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010], |
| Protein Expression | Erythrocyte,Liver,Spleen,Uterus, |
| Subcellular Localization | cytoplasm,mitochondrial outer membrane,endoplasmic reticulum membrane,membrane,integral component of membrane,intracellular membrane-bounded organelle,extracellular exosome, |
| Protein Function | disease:Defects in CYB5A are the cause of type IV hereditary methemoglobinemia [MIM:250790].,function:Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.,similarity:Belongs to the cytochrome b5 family.,similarity:Contains 1 cytochrome b5 heme-binding domain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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