ITT1258
ITT1258
- Catalog: ITT1258
- Gene/Protein: CYC1
- Product Description: Immunotag™ Cytochrome c1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Cytochrome c1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CYC1. AA range:132-181 |
| Specificity | Cytochrome c1 Polyclonal Antibody detects endogenous levels of Cytochrome c1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CYC1 |
| Accession No. | P08574 Q9D0M3 |
| Alternate Names | CYC1; Cytochrome c1; heme protein, mitochondrial; Complex III subunit 4; Complex III subunit IV; Cytochrome b-c1 complex subunit 4; Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit; Cytochrome c-1 |
| Description | cytochrome c1(CYC1) Homo sapiens This gene encodes a subunit of the cytochrome bc1 complex, which plays an important role in the mitochondrial respiratory chain by transferring electrons from the Rieske iron-sulfur protein to cytochrome c. Mutations in this gene may cause mitochondrial complex III deficiency, nuclear type 6. [provided by RefSeq, Dec 2013], |
| Cell Pathway/ Category | Oxidative phosphorylation,Cardiac muscle contraction,Alzheimer's disease,Parkinson's disease,Huntington's disease, |
| Protein Expression | Brain,Kidney,Lung,Skin, |
| Subcellular Localization | nucleus,mitochondrion,mitochondrial inner membrane,mitochondrial respiratory chain complex III,membrane,integral component of membrane,respiratory chain, |
| Protein Function | function:This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain.,PTM:Binds 1 heme group per subunit.,similarity:Belongs to the cytochrome c family.,subunit:The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1)., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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