ITT1263
ITT1263
- Catalog: ITT1263
- Gene/Protein: KRT15
- Product Description: Immunotag™ Cytokeratin 15 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | Cytokeratin 15 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat,Monkey |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from Cytokeratin 15, at AA range: 1-80 |
Specificity | Cytokeratin 15 Polyclonal Antibody detects endogenous levels of Cytokeratin 15 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | KRT15 |
Accession No. | P19012 Q61414 Q6IFV3 |
Alternate Names | KRT15; KRTB; Keratin; type I cytoskeletal 15; Cytokeratin-15; CK-15; Keratin-15; K15 |
Description | keratin 15(KRT15) Homo sapiens The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21.2. [provided by RefSeq, Jul 2008], |
Protein Expression | Pancreas,Tongue, |
Subcellular Localization | nucleus,intermediate filament,extracellular exosome, |
Protein Function | miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins.,tissue specificity:Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |