ITT1277
ITT1277
- Catalog: ITT1277
- Gene/Protein: DRD1
- Product Description: Immunotag™ D1DR Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | D1DR |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from D1DR, at AA range: 110-190 |
| Specificity | D1DR Polyclonal Antibody detects endogenous levels of D1DR protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | DRD1 |
| Accession No. | P21728 Q61616 P18901 |
| Alternate Names | DRD1; D(1A) dopamine receptor; Dopamine D1 receptor |
| Description | dopamine receptor D1(DRD1) Homo sapiens This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Calcium,Neuroactive ligand-receptor interaction,Gap junction, |
| Protein Expression | Brain, |
| Subcellular Localization | nucleus,endoplasmic reticulum membrane,plasma membrane,integral component of plasma membrane,nonmotile primary cilium,ciliary membrane, |
| Protein Function | function:This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family.,subcellular location:Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14.,subunit:Interacts with DNAJC14 via its C-terminus (By similarity). Interacts with DRD1IP.,tissue specificity:Detected in caudate, nucleus accumbens and in the olfactory tubercle., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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