ITT1302
ITT1302
- Catalog: ITT1302
- Gene/Protein: LAMP3
- Product Description: Immunotag™ DC-LAMP Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | DC-LAMP |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human LAMP3. AA range:274-323 |
Specificity | DC-LAMP Polyclonal Antibody detects endogenous levels of DC-LAMP protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | LAMP3 |
Accession No. | Q9UQV4 Q7TST5 |
Alternate Names | LAMP3; DCLAMP; TSC403; Lysosome-associated membrane glycoprotein 3; LAMP-3; Lysosomal-associated membrane protein 3; DC-lysosome-associated membrane glycoprotein; DC LAMP; Protein TSC403; CD antigen CD208 |
Description | lysosomal associated membrane protein 3(LAMP3) Homo sapiens Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]).[supplied by OMIM, Dec 2010], |
Cell Pathway/ Category | Lysosome, |
Protein Expression | Lung,Testis, |
Subcellular Localization | lysosomal membrane,early endosome,plasma membrane,membrane,integral component of membrane,vesicle,perinuclear region of cytoplasm,alveolar lamellar body membrane, |
Protein Function | function:Might change the lysosome function after the transfer of peptide-MHC class II molecules to the surface of dendritic cells.,similarity:Belongs to the LAMP family.,tissue specificity:Expressed in lymphoid organs and dendritic cells. Expressed in lung. Up-regulated in carcinomas of the esophagus, colon, rectum, ureter, stomach, breast, fallopian tube, thyroid and parotid tissues., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |