ITT1309
ITT1309
- Catalog: ITT1309
- Gene/Protein: DDX19B
- Product Description: Immunotag™ DDX19B Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | DDX19B |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human DDX19B. AA range:1-50 |
Specificity | DDX19B Polyclonal Antibody detects endogenous levels of DDX19B protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | DDX19B |
Accession No. | Q9UMR2 |
Alternate Names | DDX19B; DBP5; DDX19; TDBP; ATP-dependent RNA helicase DDX19B; DEAD box RNA helicase DEAD5; DEAD box protein 19B |
Description | DEAD-box helicase 19B(DDX19B) Homo sapiens DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
Protein Expression | Brain,Liver,Ovary,Skin,Stomach,Testis, |
Subcellular Localization | nucleus,nuclear envelope,nuclear pore,cytoplasm,membrane,nuclear membrane,extracellular exosome, |
Protein Function | function:ATP-dependent RNA helicase involved in mRNA export from the nucleus.,similarity:Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,subcellular location:Nuclear pore complex cytoplasmic fibrils.,subunit:Interacts with NUP214., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |