ITT1334
ITT1334
- Catalog: ITT1334
- Gene/Protein: DGKE
- Product Description: Immunotag™ DGK-ε Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | DGK-ε |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human DGKE. AA range:161-210 |
Specificity | DGK-ε Polyclonal Antibody detects endogenous levels of DGK-ε protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | DGKE |
Accession No. | P52429 Q9R1C6 |
Alternate Names | DGKE; DAGK5; Diacylglycerol kinase epsilon; DAG kinase epsilon; Diglyceride kinase epsilon; DGK-epsilon |
Description | diacylglycerol kinase epsilon(DGKE) Homo sapiens Diacylglycerol kinases are thought to be involved mainly in the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. When expressed in mammalian cells, DGK-epsilon shows specificity for arachidonyl-containing diacylglycerol. DGK-epsilon is expressed predominantly in testis. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Glycerolipid metabolism,Glycerophospholipid metabolism,Phosphatidylinositol signaling system, |
Protein Expression | Brain,Pooled,Prostate,Umbilical vein endothelial cell,Uterus, |
Subcellular Localization | intracellular,cytoplasm,plasma membrane,membrane,integral component of membrane, |
Protein Function | catalytic activity:ATP + 1,2-diacylglycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.,function:Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signals transmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acid composition.,similarity:Belongs to the eukaryotic diacylglycerol kinase family.,similarity:Contains 1 DAGKc domain.,similarity:Contains 2 phorbol-ester/DAG-type zinc fingers.,tissue specificity:Expressed predominantly in testis., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |