ITT1338
ITT1338
- Catalog: ITT1338
- Gene/Protein: DGKI
- Product Description: Immunotag™ DGK-ι Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | DGK-ι |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human DGKI. AA range:991-1040 |
| Specificity | DGK-ι Polyclonal Antibody detects endogenous levels of DGK-ι protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | DGKI |
| Accession No. | O75912 |
| Alternate Names | DGKI; Diacylglycerol kinase iota; DAG kinase iota; Diglyceride kinase iota; DGK-iota |
| Description | diacylglycerol kinase iota(DGKI) Homo sapiens This gene is a member of the type IV diacylglycerol kinase subfamily. Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation, producing phosphatidic acid. The specific role of the enzyme encoded by this gene is undetermined, however, it may play a crucial role in the production of phosphatidic acid in the retina or in recessive forms of retinal degeneration. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Glycerolipid metabolism,Glycerophospholipid metabolism,Phosphatidylinositol signaling system, |
| Protein Expression | Brain,Retina, |
| Subcellular Localization | intracellular,nucleus,nucleoplasm,cytoplasm,cytosol,plasma membrane,synaptic vesicle,guanyl-nucleotide exchange factor complex,neuronal cell body,dendritic spine,protein complex,axon terminus,synapse, |
| Protein Function | catalytic activity:ATP + 1,2-diacylglycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.,similarity:Belongs to the eukaryotic diacylglycerol kinase family.,similarity:Contains 1 DAGKc domain.,similarity:Contains 2 ANK repeats.,similarity:Contains 2 phorbol-ester/DAG-type zinc fingers., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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