ITT1339
ITT1339
- Catalog: ITT1339
- Gene/Protein: DGKK
- Product Description: Immunotag™ DGK-κ Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | DGK-κ |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,IF,WB,ELISA |
| Recommended Dilution | WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human DGKK. AA range:1221-1270 |
| Specificity | DGK-κ Polyclonal Antibody detects endogenous levels of DGK-κ protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | DGKK |
| Accession No. | Q5KSL6 |
| Alternate Names | DGKK; Diacylglycerol kinase kappa; DAG kinase kappa; 142 kDa diacylglycerol kinase; Diglyceride kinase kappa; DGK-kappa |
| Description | diacylglycerol kinase kappa(DGKK) Homo sapiens The protein encoded by this gene is an enzyme that phosphorylates diacylglycerol, converting it to phosphatidic acid. The encoded protein is a membrane protein and is inhibited by hydrogen peroxide. Variations in this gene have been associated with hypospadias. [provided by RefSeq, Mar 2011], |
| Subcellular Localization | cytoplasm,plasma membrane, |
| Protein Function | catalytic activity:ATP + 1,2-diacylglycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.,enzyme regulation:Inhibited in response to H(2)O(2).,function:Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA).,PTM:Phosphorylated at Tyr-78 by some member of the SRC family in response to H(2)O(2).,similarity:Belongs to the eukaryotic diacylglycerol kinase family.,similarity:Contains 1 DAGKc domain.,similarity:Contains 1 PH domain.,similarity:Contains 2 phorbol-ester/DAG-type zinc fingers.,subunit:Does not form homooligomers.,tissue specificity:Expressed in testis, and to a lesser extent in placenta., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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