ITT1342
ITT1342
- Catalog: ITT1342
- Gene/Protein: ZDHHC15
- Product Description: Immunotag™ DHHC-15 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | DHHC-15 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ZDHHC15. AA range:288-337 |
| Specificity | DHHC-15 Polyclonal Antibody detects endogenous levels of DHHC-15 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ZDHHC15 |
| Accession No. | Q96MV8 Q8BGJ0 |
| Alternate Names | ZDHHC15; Palmitoyltransferase ZDHHC15; Zinc finger DHHC domain-containing protein 15; DHHC-15 |
| Description | zinc finger DHHC-type containing 15(ZDHHC15) Homo sapiens The protein encoded by this gene belongs to the DHHC palmitoyltransferase family. Mutations in this gene are associated with mental retardatio X-linked type 91 (MRX91). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009], |
| Protein Expression | Brain,Teratocarcinoma,Trachea, |
| Subcellular Localization | Golgi apparatus,integral component of membrane,extracellular exosome, |
| Protein Function | catalytic activity:Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA.,disease:Defects in ZDHHC15 are the cause of mental retardation X-linked type 91 (MRX91) [MIM:300577]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.,domain:The DHHC domain is required for palmitoyltransferase activity.,function:Palmitoyltransferase specific for GAP43 and DLG4/PSD95.,PTM:Autopalmitoylated.,similarity:Belongs to the DHHC palmitoyltransferase family.,similarity:Contains 1 DHHC-type zinc finger.,tissue specificity:Expressed in placenta, liver, lung, kidney, heart and brain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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