ITT1344
ITT1344
- Catalog: ITT1344
- Gene/Protein: ZDHHC9
- Product Description: Immunotag™ DHHC-9 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | DHHC-9 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human ZDHHC9. AA range:315-364 |
Specificity | DHHC-9 Polyclonal Antibody detects endogenous levels of DHHC-9 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | ZDHHC9 |
Accession No. | Q9Y397 P59268 |
Alternate Names | ZDHHC9; CXorf11; ZDHHC10; ZNF379; ZNF380; CGI-89; Palmitoyltransferase ZDHHC9; Zinc finger DHHC domain-containing protein 9; DHHC-9; DHHC9; Zinc finger protein 379; Zinc finger protein 380 |
Description | zinc finger DHHC-type containing 9(ZDHHC9) Homo sapiens This gene encodes an integral membrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein forms a complex with golgin subfamily A member 7 and functions as a palmitoyltransferase. This protein specifically palmitoylates HRAS and NRAS. Mutations in this gene are associated with X-linked mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, May 2010], |
Protein Expression | Amygdala,Brain,Kidney,Muscle,Teratocarcinoma, |
Subcellular Localization | palmitoyltransferase complex,cytoplasm,endoplasmic reticulum,endoplasmic reticulum membrane,Golgi apparatus,integral component of membrane,intrinsic component of Golgi membrane, |
Protein Function | catalytic activity:Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA.,domain:The DHHC domain is required for palmitoyltransferase activity.,function:The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS.,similarity:Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.,similarity:Contains 1 DHHC-type zinc finger.,subunit:Interacts with GOLGA7.,tissue specificity:Highly expressed in kidney, skeletal muscle, brain, lung and liver. Absent in thymus, spleen and leukocytes., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |