ITT1361
ITT1361
- Catalog: ITT1361
- Gene/Protein: DMC1
- Product Description: Immunotag™ Dmc1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Dmc1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human DMC1. AA range:61-110 |
| Specificity | Dmc1 Polyclonal Antibody detects endogenous levels of Dmc1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | DMC1 |
| Accession No. | Q14565 Q61880 |
| Alternate Names | DMC1; DMC1H; LIM15; Meiotic recombination protein DMC1/LIM15 homolog |
| Description | DNA meiotic recombinase 1(DMC1) Homo sapiens This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013], |
| Protein Expression | Ovary,Testis,Thymus, |
| Subcellular Localization | chromosome, telomeric region,condensed nuclear chromosome,nucleus,nucleoplasm,chromosome, |
| Protein Function | function:May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.,similarity:Belongs to the recA family. DMC1 subfamily.,similarity:Contains 1 HhH domain.,subunit:Interacts with the MND1-PSMC3IP heterodimer (By similarity). Double stacked ring-shaped homooctamer., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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