ITT1372
ITT1372
- Catalog: ITT1372
- Gene/Protein: POLD3
- Product Description: Immunotag™ DNA pol δ3 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | DNA pol δ3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human POLD3. AA range:411-460 |
| Specificity | DNA pol δ3 Polyclonal Antibody detects endogenous levels of DNA pol δ3 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | POLD3 |
| Accession No. | Q15054 Q9EQ28 |
| Alternate Names | POLD3; KIAA0039; DNA polymerase delta subunit 3; DNA polymerase delta subunit p66 |
| Description | DNA polymerase delta 3, accessory subunit(POLD3) Homo sapiens This gene encodes the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012], |
| Cell Pathway/ Category | Purine metabolism,Pyrimidine metabolism,DNA replication,Base excision repair,Nucleotide excision repair,Mismatch repair,Homologous recombination, |
| Protein Expression | Bone marrow,Brain,Duodenum,Embryonic kidney,Epithelium,Lymp |
| Subcellular Localization | nucleus,nucleoplasm,mitochondrion,delta DNA polymerase complex, |
| Protein Function | function:Required for optimal DNA polymerase delta activity.,subunit:Heterotetramer composed of subunits of 125 kDa, 50 kDa, 66 kDa and 12 kDa. Interacts with POLD2. Interacts with PCNA., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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