ITT1379
ITT1379
- Catalog: ITT1379
- Gene/Protein: DNAJB4
- Product Description: Immunotag™ DnaJB4 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | DnaJB4 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human DNAJB4. AA range:91-140 |
| Specificity | DnaJB4 Polyclonal Antibody detects endogenous levels of DnaJB4 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | DNAJB4 |
| Accession No. | Q9UDY4 Q9D832 |
| Alternate Names | DNAJB4; DNAJW; HLJ1; DnaJ homolog subfamily B member 4; Heat shock 40 kDa protein 1 homolog; HSP40 homolog; Heat shock protein 40 homolog; Human liver DnaJ-like protein |
| Description | DnaJ heat shock protein family (Hsp40) member B4(DNAJB4) Homo sapiens The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015], |
| Protein Expression | Aorta endothelial cell,Embryonic kidney,Liver,Lymph |
| Subcellular Localization | nucleoplasm,cytoplasm,cytosol,plasma membrane,extracellular exosome, |
| Protein Function | induction:By heat shock.,similarity:Contains 1 J domain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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