ITT1415
ITT1415
- Catalog: ITT1415
- Gene/Protein: ECI2
- Product Description: Immunotag™ DRS-1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | DRS-1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PECI. AA range:73-122 |
| Specificity | DRS-1 Polyclonal Antibody detects endogenous levels of DRS-1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ECI2 |
| Accession No. | O75521 Q9WUR2 |
| Alternate Names | ECI2; DRS1; HCA88; PECI; Enoyl-CoA delta isomerase 2; mitochondrial; DRS-1; Delta(3),delta(2)-enoyl-CoA isomerase; D3,D2-enoyl-CoA isomerase; Diazepam-binding inhibitor-related protein 1; DBI-related protein 1; Dodecenoyl-CoA isomerase; Hep |
| Description | enoyl-CoA delta isomerase 2(ECI2) Homo sapiens This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2011], |
| Cell Pathway/ Category | Fatty acid metabolism, |
| Protein Expression | Aorta endothelial cell,Brain,Cerebellum,Hepatocellular carcinoma,Hepatoma,H |
| Subcellular Localization | nucleoplasm,mitochondrion,peroxisomal matrix,membrane,intracellular membrane-bounded organelle, |
| Protein Function | catalytic activity:(3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl-CoA.,function:Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species.,similarity:Contains 1 ACB (acyl-CoA-binding) domain.,similarity:In the C-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.,tissue specificity:Abundant in heart, skeletal muscle and liver., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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