ITT1425
ITT1425
- Catalog: ITT1425
- Gene/Protein: DVL3
- Product Description: Immunotag™ Dvl-3 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Dvl-3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human DVL3. AA range:326-375 |
| Specificity | Dvl-3 Polyclonal Antibody detects endogenous levels of Dvl-3 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | DVL3 |
| Accession No. | Q92997 Q61062 |
| Alternate Names | DVL3; KIAA0208; Segment polarity protein dishevelled homolog DVL-3; Dishevelled-3; DSH homolog 3 |
| Description | dishevelled segment polarity protein 3(DVL3) Homo sapiens This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | WNT,WNT-T CELLNotch,Melanogenesis,Pathways in cancer,Colorectal cancer,Basal cell carcinoma, |
| Protein Expression | Bone marrow,Brain,Hippocampus,Placenta,Uterus, |
| Subcellular Localization | nuclear chromatin,intracellular,cytosol,Wnt signalosome, |
| Protein Function | function:May play a role in the signal transduction pathway mediated by multiple Wnt genes.,similarity:Belongs to the DSH family.,similarity:Contains 1 DEP domain.,similarity:Contains 1 DIX domain.,similarity:Contains 1 PDZ (DHR) domain.,subunit:Interacts (via the PDZ domain) with the C-terminal regions of VANGL1 and VANGL2 (By similarity). Interacts (via the region containing both the PDZ and DEP domains) with LRRFIP2; the DIX domain may inhibit this interaction., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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