ITT1519
ITT1519
- Catalog: ITT1519
- Gene/Protein: EIF5
- Product Description: Immunotag™ eIF5 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | EIF5 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from the Internal region of human eIF5 |
| Specificity | eIF5 Polyclonal Antibody detects endogenous levels of eIF5 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | EIF5 |
| Accession No. | P55010 P59325 Q07205 |
| Alternate Names | EIF5; Eukaryotic translation initiation factor 5; eIF-5 |
| Description | eukaryotic translation initiation factor 5(EIF5) Homo sapiens Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).[supplied by OMIM, May 2010], |
| Protein Expression | Brain,Epithelium,Lymph,Pooled,Uterus, |
| Subcellular Localization | nucleus,cytoplasm,cytosol,plasma membrane,cell-cell adherens junction, |
| Protein Function | function:Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).,similarity:Belongs to the eIF-2-beta/eIF-5 family.,similarity:Contains 1 W2 domain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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